2-Deoxy-2-iodo-alpha-mannopyranosyl and -talopyranosyl acetates: highly stereoselective glycosyl donors for the synthesis of 2-deoxy-alpha-glycosides.
2-Deoxy-2-iodo-alpha-mannopyranosyl and -talopyranosyl acetates: highly stereoselective glycosyl donors for the synthesis of 2-deoxy-alpha-glycosides.
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DOI：
10.1021/ol9908068
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发表时间：
1999-08
期刊：
影响因子：
5.2
通讯作者：
W. Roush;S. Narayan
中科院分区：
文献类型：
--
作者：
W. Roush;S. Narayan
[公式：2-脱氧-2-碘-α-吡喃甘露糖基乙酸酯8-10和2-脱氧-2-碘-α-吡喃塔罗糖基乙酸酯11的TMS-OTf-或TBS-OTf-促进的糖苷化反应提供相应的2-脱氧-2-碘-α-吡喃糖苷，2-脱氧-α-糖苷的前体，作为唯一观察到的反应产物。
[formula: see text] TMS-OTf- or TBS-OTf-promoted glycosidation reactions of 2-deoxy-2-iodo-alpha-mannopyranosyl acetates 8-10 and the 2-deoxy-2-iodo-alpha-talopyranosyl acetate 11 provide the corresponding 2-deoxy-2-iodo-alpha-pyranosides, precursors to 2-deoxy-alpha-glycosides, as the only observed reaction products.