Peste des petits ruminants virus (PPRV) infection; Its association with species, seasonal variations and geography
Peste des petits ruminants virus (PPRV) infection; Its association with species, seasonal variations and geography
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DOI：
10.1007/s11250-008-9300-9
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发表时间：
2009-10-01
影响因子：
1.7
通讯作者：
Ali, Qurban
中科院分区：
文献类型：
--
作者：
Abubakar, Muhammad;Jamal, Syed Muhammad;Ali, Qurban
本次调查详细描述了与巴基斯坦 PPRV 感染直接相关的因素。对总共 1,056 份疑似血清样本进行了分析，以确定是否存在 PPRV 抗体，且无 PPR 疫苗接种史。这些样本是从全国二十五 (25) 个主要地区的六十二 (62) 起疑似疫情中采集的。从患有腹泻并表现出严重呼吸道症状的动物身上采集样本。进行竞争性酶联免疫吸附测定（cELISA）来检测血清中是否存在抗 PPRV 抗体。研究结果表明，绵羊中记录的 PPR 抗体总体血清流行率为 54.09%，而山羊中为 44.15%。地理、物种、性别、年龄和季节是PPRV感染的主要因素。在不同年龄组中，与其他年龄组相比，2岁以上动物的患病率较高（绵羊和山羊分别为67.48%和52.28%）。各地区血清流行率最高的是信德省，为 55.10%。旁遮普省和信德省的平原以及丘陵地区（AJK、北部地区和旁遮普省北部）的气温最高。这些发现可能与不同地理区域内绵羊和山羊饲养方式以及不同地区地形的差异有关。该研究还表明了抗体在人群中循环的情况，并证明小反刍兽疫现在正在流行，并且是巴基斯坦主要的新兴跨界动物疫病之一。
The present investigation included a detailed description of the factors directly associated with PPRV infection in Pakistan. A total of 1,056 suspected serum samples were analyzed for the presence of antibodies to PPRV with no history of vaccination against PPR. The samples were collected from sixty two (62) suspected outbreaks from twenty five (25) major regions of the country. Samples were collected from the animals suffering from diarrhea and showing severe respiratory signs. Competitive enzyme linked immuno-sorbant assay (cELISA) was performed to detect the presence of antibodies in the serum against PPRV. Findings suggested that the overall PPR antibody sero-prevalence recorded in sheep was 54.09% as compared to 44.15% in goats. Geography, species, sex, age and season are the major factors associated with PPRV infection. Among various age groups, the animals showed the higher prevalence (67.48% and 52.28% in sheep and goats, respectively) at > 2 years as compared with the other age groups. The area-wise highest sero-prevalence was in Sindh province which was 55.10%. It was highest in the plains of Punjab and Sindh province and also in hilly areas (AJK, northern areas and northern Punjab). These findings may be correlated with variations in the sheep and goats husbandry practices within different geographic regions and the topography of different areas. The study also indicated the scenario of antibodies circulation in the population and proving that PPR is now becoming endemic and is one of the major emerging TAD in Pakistan.