Clinical Characteristics and Early Visual Outcomes of Highly Myopic Cataract Eyes: The Shanghai High Myopia Study.
Clinical Characteristics and Early Visual Outcomes of Highly Myopic Cataract Eyes: The Shanghai High Myopia Study.
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高度近视白内障眼的临床特征和早期视力结果：上海高度近视研究
DOI：
10.3389/fmed.2021.671521
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发表时间：
2021
影响因子：
3.9
通讯作者：
Lu Y
中科院分区：
文献类型：
--
作者：
He W;Yao Y;Zhang K;Du Y;Qi J;Zhang Y;Zhang S;Zhao Z;Cai L;Fan Q;Jiang Y;Yang J;Zhu X;Lu Y
目的：报道高度近视白内障患者的眼部特征和早期视力预后，分析低视力的危险因素。研究方法：对复旦大学附属眼耳鼻喉科医院在上海高度近视研究中登记的1,400例眼轴长度（AL）≥ 26 mm的白内障患者的2,027只眼进行分析。术前行常规眼科检查，行黄斑部光学相干断层扫描（OCT）。通过OCT图像评价黄斑并发症、中心凹厚度（CFT）和中心凹下脉络膜厚度（SFCT）。同时记录眼部和手术史及围手术期并发症。评价术后1个月裸眼视力和最佳矫正视力（UCVA/BCVA）及其影响因素。结果如下：所有患眼的平均AL为29.52 ± 2.26mm，其中39.7%的患者AL > 30 mm，26.4%的患者角膜散光> 1.5D。核性白内障占70.6%。总的黄斑并发症发生率为27.6%。术后UCVA和BCVA分别为0.70 ± 0.46和0.25 ± 0.32 logMAR。术后最佳矫正视力明显提高（P < 0.001），且受AL延长（P < 0.001）和CFT、SFCT变薄（均P < 0.001）的影响。术后低视力（BCVA < 20/66）的危险因素为黄斑萎缩、黄斑板层裂孔、高度角膜散光、长AL、薄SFCT和低年资手术者，OR值为1.54 ~ 54.87（均P < 0.05）。结论：高度近视眼白内障手术可提高视力。患有黄斑并发症、角膜散光较高、AL较长、SFCT较薄且由初级外科医生治疗的眼睛，术后低视力的风险较高。
Purpose: To report ocular characteristics and early visual outcomes of highly myopic cataract eyes, and to analyze the risk factors of low vision. Methods: A total of 2,027 eyes of 1,400 cataract patients with axial length (AL) ≥ 26 mm undergoing cataract surgery in Eye & ENT Hospital of Fudan University, who were registered in the Shanghai High Myopia Study, were analyzed. Routine pre-operative ophthalmic examinations were performed and macular scan of optical coherence tomography (OCT) were obtained. Macular complications, central foveal thickness (CFT) and subfoveal choroidal thickness (SFCT) were evaluated from OCT images. Ocular and surgical history and perioperative complications were also recorded. Uncorrected and best-corrected visual acuity (UCVA/BCVA) 1 month post-operatively and its influencing factors were evaluated. Results: The average AL of all involved eyes was 29.52 ± 2.26 mm, and 39.7% of which were with an AL > 30 mm and 26.4% of which were with a corneal astigmatism more than 1.5 D. Nuclear cataract accounted for the largest proportion (70.6%). The rate of overall macular complications was 27.6%. Postoperative UCVA and BCVA were 0.70 ± 0.46 and 0.25 ± 0.32 logMAR, respectively. BCVA improved significantly after surgery (vs. P < 0.001) and affected by the elongation of AL (P < 0.001) and thinning of CFT and SFCT (both P < 0.001). The risk factors of post-operative low vision (BCVA < 20/66) were macular atrophy, lamellar macular hole, high corneal astigmatism, long AL, thin SFCT and junior surgeons, odds ratios ranging from 1.54 to 54.87 (all P < 0.05). Conclusion: Cataract surgery could improve the VA of highly myopic eyes. Eye with macular complications, higher corneal astigmatism, longer AL, thinner SFCT, and who was treated by a junior surgeon, may have a high risk of low vision after surgery.
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作者：
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通讯作者：
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DOI：
10.1007/s00417-012-2043-3
发表时间：
2013-02-01
影响因子：
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影响因子：
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高度近视韩国人白内障手术的临床特征和结果。
影响因子：
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作者：
Jeon S;Kim HS
通讯作者：
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影响因子：
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作者：
Zhu XJ;Zhou P;Zhang KK;Yang J;Luo Y;Lu Y
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