Characterization of binding interactions by isothermal titration calorimetry
Characterization of binding interactions by isothermal titration calorimetry
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DOI：
10.1016/s0958-1669(97)80154-1
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发表时间：
1997-02-01
影响因子：
7.7
通讯作者：
Doyle, ML
中科院分区：
文献类型：
--
作者：
Doyle, ML
等温滴定量热法是一种用于测量结合亲和力的高精度方法。滴定量热法是一种通用的方法，在整个生物技术中具有广泛的影响。近年来，能够表征生物大分子的结合相互作用的微量热计已经商业化。这些研究的结果为大分子相互作用的分子本质提供了新的见解。
Isothermal titration calorimetry is a high-accuracy method for measuring binding affinities. Titration calorimetry is a universal method that has broad impact throughout biotechnology. In recent years, microcalorimeters that are capable of characterizing binding interactions of biological macromolecules have become commercially available. Results from these studies are providing new insight into the molecular nature of macromolecular interactions.