Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scale
Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scale
复制标题
DOI：
10.1310/jfxh-g3x2-eym6-d6ug
复制
发表时间：
2004-03-01
影响因子：
--
通讯作者：
Bangsberg, DR
中科院分区：
文献类型：
--
作者：
Giordano, TP;Guzman, D;Bangsberg, DR
目的：使用居住地未公布的药丸数量作为金标准，与基于 3 天回忆的仪器相比，检查基于视觉模拟量表评估依从性的仪器的性能。方法：我们前瞻性地评估了 84 名在加利福尼亚州旧金山接受稳定抗逆转录病毒治疗的边缘贫困艾滋病毒感染者的抗逆转录病毒治疗依从性，在不超过 4 个月的时间里进行了 3 次依从性评估。结果：使用视觉模拟量表、3 天回忆和突击药丸计数方法的平均依从性分别为 82.5%、84.2% 和 75.9%。视觉模拟量表与未公布的药丸计数之间的相关性很高 (r = 0.76)，并且与 3 天回忆和未公布的药丸计数之间的相关性没有统计学差异 (r = 0.71；p =.52)。两种方法也同样与 HIV 病毒载量呈负相关（分别为 r = -0.49 和 -0.34；相关性差异 p = 0.22）。视觉模拟量表与未公布的药丸计数的相关性随着时间的推移保持稳定，并且在所有检查的亚人群中保持较高水平。结论：在这个多样化的人群中，使用视觉模拟量表以及更复杂的 3 天回忆工具来评估依从性。鉴于其简单性，视觉模拟量表依从性仪器将在研究中有用，并且可能在常规患者护理中有用。
Purpose: To examine the performance of an instrument to assess adherence based on a visual analogue scale, compared to an instrument based on 3-day recall, using unannounced pill counts in the place of residence as the gold standard. Method: We prospectively assessed adherence to antiretroviral therapy in 84 marginally housed indigent HIV-infected patients who were receiving stable antiretroviral therapy in San Francisco, California, with three adherence assessments over no more than 4 months. Results: Mean adherence using the visual analogue scale, 3-day recall, and unannounced pill count methods were 82.5%, 84.2%, and 75.9%, respectively. The correlation between visual analogue scale and unannounced pill count was high (r = 0.76) and was not statistically different from that between 3-day recall and unannounced pill count (r = 0.71; p =.52). Both methods were also similarly inversely correlated with HIV viral load (r = -0.49 and -0.34, respectively; p = .22 for the difference in the correlations). The visual analogue scale correlation with unannounced pill count was stable over time and remained high in all subpopulations examined. Conclusion: A visual analogue scale to assess adherence was performed as well as a more complicated 3-day recall instrument in this diverse population. Given its simplicity, the visual analogue scale adherence instrument will be useful in research and may be useful in routine patient care.