deficiency: an anatomic study. predict vulnerability to perfusion or oxygenation Features of the cerebral vascular pattern that
deficiency: an anatomic study. predict vulnerability to perfusion or oxygenation Features of the cerebral vascular pattern that
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通讯作者：
D. M. Moody;M. A. Bell;V. Challa;D. M. Moody1
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作者：
D. M. Moody;M. A. Bell;V. Challa;D. M. Moody1
在一项正在进行的人类脑微血管解剖研究中，我们有机会分析这种血管供应的总体方案。天然的内皮膜酶，碱性磷酸酶，用于在血管壁上沉淀黑色硫化铅盐，使大脑微血管在光学显微镜和显微放射照相下可见。对幕上脑的实质内传入血液供应有六种不同的模式：来自单一来源的短动脉（例如，皮层中的小动脉）；短至中等长度的小动脉，单一来源（胼胝体前三分之二）；短至中等长度的小动脉和动脉，双来源（皮质下U纤维）；中等长度的小动脉和动脉，三源（端/外囊和屏状突）；长动脉和小动脉，单一来源（半瓣中心）；大而长的肌肉动脉，单一来源（丘脑和基底神经节）。这种安排的本质为大脑的某些区域提供了一些保护，使其免受低血压等循环挑战，同时使其他区域易受伤害。远端小动脉
In an ongoing study of brain microvasculature in humans at autopsy, we had the opportunity to analyze the overall scheme of this vascular supply. The native endothelial membrane enzyme, alkaline phosphatase, is used to precipitate black lead sulfide salt in the vessel wall, rendering the brain microvasculature visible by both light microscopy and microradiography. There are six distinct patterns of intraparenchymal afferent blood supply to the supratentorial brain: short arterioles from a single source (e.g., those in the cortex); short-to intermediate-length arterioles, single source (anterior two-thirds of the corpus callosum); short-to intermediate-length arterioles and arteries, dual source (subcortical U fibers); intermediate-length arterioles and arteries, triple source (extreme/ external capsule and claustrum); long arteries and arterioles, single source (centrum semiovale); and large, long muscular arteries, single source (thalamus and basal ganglia). The nature of this arrangement offers some protection to certain regions of the cerebrum from circulatory challenges such as hypotension, while leaving other areas vulnerable. The distal arterioles