Local control and site of failure in radically irradiated supraglottic laryngeal cancer.
Local control and site of failure in radically irradiated supraglottic laryngeal cancer.
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彻底照射的声门上喉癌的局部控制和失败部位。
DOI：
10.1148/112.1.187
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发表时间：
1974
期刊：
影响因子：
19.7
通讯作者：
V. Krishnaswamy
中科院分区：
文献类型：
--
作者：
N. Ghossein;J. Bataini;A. Ennuyer;P. Stacey;V. Krishnaswamy
应用时间-剂量散点图和标称标准剂量(NSD)分析203例声门上型喉癌根治性放疗后的局部控制情况和并发症。早期(T-1、T-2)肿瘤呈剂量-反应曲线，晚期(T-3、T-4)肿瘤未见剂量-反应曲线。所有直径小于2.5 cm的结节均控制在7000rad。在早期病变中，89%的患者在6周内接受了7700拉德的照射后得到控制。原发灶治愈后85%以上受累结节得到控制。主要并发症发生率均未超过7%。
The local control and complications after radical irradiation were analyzed in 203 patients with supraglottic cancer, using time-dose scattergrams and nominal standard dose (NSD). A dose-response curve was obtained for early (T-1, T-2) tumors but was not demonstrated in advanced neoplasms (T-3, T-4). All nodes less than 2.5 cm in diameter were controlled with 7,000 rads. Of the early lesions 89% were controlled with 7,700 rads in six weeks. Over 85% of the involved nodes were controlled when the primary was cured. The incidence of major complications did not exceed 7%.