Periodontal treatment of patients with Papillon-Lefevre syndrome: a 3-year follow-up

Periodontal treatment of patients with Papillon-Lefevre syndrome: a 3-year follow-up
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DOI:
10.1111/j.1600-051x.2004.00591.x
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发表时间:
2004-11-01
影响因子:
6.7
通讯作者:
Renvert, S
Renvert, S
中科院分区:
医学1区
文献类型:
--
作者:
Lundgren, T;Renvert, S

文献摘要

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背景/目的:传统的机械牙周治疗的Papillon-Lefevre综合征(PLS)经常被报道失败。本研究描述了非手术牙周治疗的结果,包括抗菌治疗的9名患者诊断为PLS。患者来自共15名儿童和青少年PLS的临床特点presented.Methods:临床检查,包括传统的牙周测量。初始治疗包括口腔卫生指导、洁治、根面平整和全身阿莫西林-甲硝唑治疗6周。之后,患者被纳入为期3个月的召回维持计划。除了这种机械支持性维护治疗,四环素规定,并连续使用1.5 years.Results/Conclusion:在5例患者谁表现出可接受的标准的口腔卫生和遵守抗生素药物治疗,牙周炎的发展上萌出的牙齿预防和疾病活动的以前牙周参与的牙齿控制在3年期间。观察到三名患者的治疗结果不佳,均为兄弟姐妹。这些患者未能遵守药物治疗,也未能改善口腔卫生。
Background/aim: Conventional mechanical periodontal treatment of Papillon-Lefevre syndrome (PLS) has often been reported to fail. This study describes the outcome of a non-surgical periodontal therapy including antimicrobial treatment of nine patients diagnosed with PLS. The patients originate from a total of 15 children and adolescents with PLS for which clinical characteristics are presented.Methods: Clinical examination including conventional periodontal measurements. Initial treatment including oral hygiene instruction, scaling and root planing and systemic amoxicillin-metronidazole therapy for 6 weeks. After that the patients were enrolled in a 3-month recall maintenance program. In addition to this mechanical supportive maintenance treatment, tetracycline was prescribed and used continuously for 1.5 years.Results/Conclusion: On five patients who were showing acceptable standard of oral hygiene and also compliance with the antibiotic medication, development of periodontitis on erupting teeth was prevented and disease activity on the previously periodontally involved teeth controlled during a 3-year period. Poor results of treatment were observed for three patients, all siblings. These patients failed to comply with the medication and also failed to improve their oral hygiene.