Update on the genetic effects of ionizing radiation.
Update on the genetic effects of ionizing radiation.
复制标题
电离辐射遗传效应的最新进展。
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
J. Neel
中科院分区：
文献类型：
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作者：
J. Neel
公众仍然十分关注人类受到辐射的遗传影响。加德纳及其同事去年的报告极大地激发了人们对这一问题的兴趣。为了了解英国西坎布里亚郡塞拉菲尔德核电站附近报告的儿童白血病和淋巴瘤的过量情况，这些研究人员进行了一项病例对照研究，以了解环境与这些疾病的关系。该研究确定了52例白血病，22例非霍奇金淋巴瘤和23例霍奇金病，所有病例均发生在25岁以下。对于每种情况，使用多达8个对照。由于许多关联性检验是重叠的，因此很难推断出进行了多少次独立的统计检验，但似乎至少有70次。最重要的发现是，患白血病的孩子的父亲
The genetic implications of human exposures to radiation continue to be very much on the public mind. Interest in the issue was greatly stimulated by the report of Gardner and associates 1 last year. In an effort to understand the excess of childhood leukemia and lymphoma reported in the vicinity of the Sellafield nuclear plant in the West Cumbria district of the United Kingdom, these investigators conducted a case-control study for environmental associations with these diseases. The study identified 52 cases of leukemia, 22 of non-Hodgkin's lymphoma, and 23 of Hodgkin's disease, all occurring under 25 years of age. For each case, up to eight controls were used. Because many of the tests for associations are overlapping, it is difficult to deduce how many independent statistical tests were performed, but it appears to be at least 70. The most significant finding was that the fathers of children who developed leukemia
人类和小鼠的比较辐射遗传学。
影响因子：
11.1
作者：
Neel,JV;Lewis,SE
通讯作者：
Lewis,SE