Some experiences of techniques for stimulation of the human cerebral motor cortex through the scalp.
Some experiences of techniques for stimulation of the human cerebral motor cortex through the scalp.
复制标题
通过头皮刺激人大脑运动皮层技术的一些体会。
作者：
J. Rothwell;B. Day;P. Thompson;J. Dick;C. Marsden
经颅刺激运动皮质显示出头皮上与小人相对应的刺激部位的粗略体位和对侧手部肌肉的优先激活，以及颈髓中信号的非常短的潜伏期。肌肉的背景激活也促进了这些反应。我们报告了一组患者，采用经颅电刺激和磁刺激进行研究。我们观察到，肌电活动的潜伏期比收缩肌肉短得多，皮质刺激产生的肌肉抽动可以超过超最大刺激周围神经产生的力量。我们的发现表明，这可能是由于运动神经元的多次放电所致。另一个观察结果是，磁刺激的反应潜伏期并不比电刺激的反应潜伏期长2毫秒。对这些发现的意义进行了讨论。
Stimulation of the motor cortex transcranially has shown a rough somatotopy of stimulation sites on the scalp corresponding to the homunculus and preferential activation of contralateral hand muscles, as well as very short latencies of signals in the cervical spinal cord. The responses are also facilitated by background activation of the muscles. We are reporting a set of patients studied using electrical and magnetic stimulation transcranially. We observed that the latency of electromyogram activation is much shorter in active than contracting muscles and that the muscle twitch produced by cortical stimulation can exceed the force produced by supramaximal stimulation of the peripheral nerve. Our findings suggest that this may be due to multiple firing of motor neurons. Another observation is that magnetic stimulation is not as subject to a reduction in the response latency with facilitation, and response latencies with magnetic stimulation were 2 ms longer than with electrical stimulation. The implications of these findings are discussed.