Spectrum of ultraviolet radiation on human B and T lymphocyte viability
Spectrum of ultraviolet radiation on human B and T lymphocyte viability
复制标题
紫外线辐射光谱对人 B 和 T 淋巴细胞活力的影响
DOI：
10.1111/j.1365-2230.1978.tb01458.x
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发表时间：
1978
影响因子：
4.1
通讯作者：
R. Hong
中科院分区：
文献类型：
--
作者：
D. Cripps;S. Horowitz;R. Hong
用不同波长的紫外线照射人淋巴细胞。使用0·1 - 0·067 J/cm 2剂量的UVC（杀菌灯）或254 nm单色辐射实现选择性T细胞杀伤，同时保留B细胞功能。用高达9 J/cm 2的UVA照射淋巴细胞没有引起明显的T和B细胞杀伤。单色280和296 nm辐射（UVB）的照射显示T和B细胞的敏感性相似，在低于0·5 J/cm 2时发生杀伤。
Human lymphocytes were irradiated with ultraviolet radiation (UV) of various wavelengths. Selective T cell killing was achieved with a dose of 0·1‐0·067 J/cm2 with UVC (a germicidal lamp) or 254 nm monochromatic radiation while preserving B cell function. Irradiation of lymphocytes with UVA up to 9 J/cm2 caused no apparent T and B cell killing. Irradiation with monochromatic 280 and 296 nm radiation (UVB) showed similar susceptibility of both T and B cells with killing occurring with less than 0·5 J/cm2.