Risk Factors Associated With Skin and Soft Tissue Infections Among Hospitalized People Who Inject Drugs
Risk Factors Associated With Skin and Soft Tissue Infections Among Hospitalized People Who Inject Drugs
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DOI：
10.1097/adm.0000000000000346
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发表时间：
2017-11-01
影响因子：
5.5
通讯作者：
Stein, Michael D.
中科院分区：
文献类型：
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作者：
Phillips, Kristina T.;Anderson, Bradley J.;Stein, Michael D.
目的：皮肤和软组织感染 (SSTI) 在注射吸毒者 (PWID) 中很常见，可导致严重的发病率和昂贵的急诊室和医院使用费用。一系列高风险注射行为可能会导致这些感染。本研究的目标是检查住院注射吸毒者样本中与 SSTI 相关的风险做法。方法：从一家大型城市医院的住院医疗单位招募注射吸毒者（N = 143；40.6% 女性），并完成关注感染风险的基线访谈。衡量指标包括人口统计、使用/注射的物质以及过去一年内 SSTI（即脓肿、溃疡或蜂窝织炎）的自我报告。注射者细菌感染风险量表的 7 项指标评估了预计会增加感染 SSTI 风险的特定行为（例如，未经皮肤清洁的注射、肌肉注射）。 结果：样本为 58% 白人，平均年龄 38.7 (SD=10.7) 岁。 93 名参与者 (65%) 报告在过去一年内至少发生过 1 次 SSTI。使用逻辑回归模型，注射者细菌感染风险量表（比值比 1.87，P=0.004）和过去 3 个月的注射总数（比值比 2.21，P=0.002）与过去一年的 SSTI 相关。结论：总而言之，在该住院注射吸毒者样本中，过去一年的 SSTI 发生率较高。结果表明，干预措施应针对特定的注射实践，以降低感染风险。
Objectives:Skin and soft tissue infections (SSTIs) are common among people who inject drugs (PWID), and can lead to serious morbidity and costly emergency room and hospital utilization. A range of high-risk injection practices may contribute to these infections. The goal of the current study was to examine risk practices that were associated with SSTIs in a sample of hospitalized PWID.Methods:PWID (N=143; 40.6% female) were recruited from inpatient medical units at a large urban hospital and completed a baseline interview that focused on infection risk. Measures included demographics, substances used/injected, and self-report of SSTIs (ie, abscesses, ulcers, or cellulitis) within the past year. The Bacterial Infections Risk Scale for Injectorsa 7-item indexassessed specific behaviors expected to increase the risk of acquiring SSTIs (eg, injection without skin cleaning, intramuscular injection).Results:The sample was 58% Caucasian and averaged 38.7 (SD=10.7) years of age. Ninety-three participants (65%) reported at least 1 SSTI within the past year. Using a logistic regression model, the Bacterial Infections Risk Scale for Injectors (odds ratio 1.87, P=0.004) and total number of injections over the past 3 months (odds ratio 2.21, P=0.002) were associated with past year SSTIs.Conclusions:In conclusion, rates of past-year SSTIs were high in this sample of hospitalized PWID. Results suggest that interventions should target specific injection practices to reduce infection risk.