Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: A quantitative review
Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: A quantitative review
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DOI：
10.1037/0022-006x.65.1.44
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发表时间：
1997-02-01
影响因子：
5.9
通讯作者：
Abramowitz, JS
中科院分区：
文献类型：
--
作者：
Abramowitz, JS
对强迫症（OCD）的对照治疗结果文献的定量审查表明，暴露与反应预防在减少强迫症症状方面非常有效。认知方法也被发现至少与暴露程序一样有效。看来认知和暴露干预都涉及一些重叠的程序，并利用类似的变化机制。5-羟色胺能药物，特别是氯丙咪嗪，也大大减少了强迫症的症状。然而，氯丙咪嗪可能并不特别上级其他肾上腺素能药物。探讨了药物试验中副作用与效应量的关系。
Quantitative review of the controlled treatment outcome literature for obsessive-compulsive disorder (OCD) showed that exposure with response prevention was highly effective in reducing OCD symptoms. Cognitive approaches were also found to be at least as effective as exposure procedures. It appears that both cognitive and exposure interventions involve some overlapping procedures and capitalize on similar mechanisms of change. Serotonergic medication, particularly clomipramine, also substantially reduced OCD symptoms. However, clomipramine may not be particularly superior to other serotonergic medication. The relationship between side effects and effect size in medication trials was explored.