Sonochemical fabrication of Fe3O4 nanoparticles on reduced graphene oxide for biosensors
Sonochemical fabrication of Fe3O4 nanoparticles on reduced graphene oxide for biosensors
复制标题
声化学法在还原氧化石墨烯上制备 Fe3O4 纳米颗粒用于生物传感器
DOI：
10.1016/j.ultsonch.2012.12.001
复制
发表时间：
2013-05-01
影响因子：
8.4
通讯作者：
Ma, Jun
中科院分区：
文献类型：
--
作者：
Zhu, Shenmin;Guo, Jingjing;Ma, Jun
采用超声化学法制备了粒径为30-40 nm的Fe3O4纳米粒子，并将其均匀分散在还原氧化石墨烯片（Fe3O4/RGO）上。样品振动磁强计测试表明，Fe_3O_4/RGO的饱和磁化强度为30 emu/g。根据实验结果，我们提出了超声波作用机理来解释Fe3O4纳米颗粒在RGO表面的形成和分散。将Fe3O4/RGO与血红蛋白复合修饰在玻碳电极上，制备了血红蛋白生物传感器。该生物传感器对H2O2具有良好的电催化还原性能，检测限为2 × 10（-6）M，线性范围为4 × 10（-6）~1 × 10（-3）M（R-2 = 0.994）。H2O2检测的高性能归因于Fe3O4纳米颗粒和RGO的组合的协同效应，促进过氧化物和电极表面之间的电子转移。(C)2012爱思唯尔有限公司版权所有。
This study synthesized Fe3O4 nanoparticles of 30-40 nm by a sonochemical method, and these particles were uniformly dispersed on the reduced graphene oxide sheets (Fe3O4/RGO). The superparamagnetic property of Fe3O4/RGO was evidenced from a saturated magnetization of 30 emu/g tested by a sample-vibrating magnetometer. Based on the testing results, we proposed a mechanism of ultrasonic waves to explain the formation and dispersion of Fe3O4 nanoparticles on RGO. A biosensor was fabricated by modifying a glassy carbon electrode with the combination of Fe3O4/RGO and hemoglobin. The biosensor showed an excellent electrocatalytic reduction toward H2O2 at a wide, linear range from 4 x 10(-6) to 1 x 10(-3) M (R-2 = 0.994) as examined by amperometry, and with a detection limit of 2 x 10(-6) M. The high performance of H2O2 detection is attributed to the synergistic effect of the combination of Fe3O4 nanopartides and RGO, promoting the electron transfer between the peroxide and electrode surface. (C) 2012 Elsevier B.V. All rights reserved.