Vitamin D: a D-Lightful health perspective

Vitamin D: a D-Lightful health perspective
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DOI:
10.1111/j.1753-4887.2008.00104.x
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发表时间:
2008-10-01
期刊:
影响因子:
6.1
通讯作者:
Holick, Michael F.
Holick, Michael F.
中科院分区:
医学2区
文献类型:
--
作者:
Holick, Michael F.

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阳光为大多数人提供所需的维生素D。通过皮肤合成或从饮食和补充来源获得足够的维生素D-3对一生中骨骼健康至关重要。维生素D缺乏症定义为25(OH)D浓度< 20 ng/mL (50 nmol/L);维生素D充足为25(OH)D bb0 30 ng/mL (75 nmol/L),不足为21-29 ng/mL。维生素D缺乏和不足与多种慢性疾病有关,包括常见的癌症、自身免疫性疾病、心血管疾病和传染病。卫生保健专业人员需要意识到维生素D缺乏症的流行。合理的阳光照射和每天800-1000国际单位的维生素D补充指南是必要的。(C) 2008年国际生命科学研究所。
Sunlight provides most humans with their vitamin D requirement. Adequate vitamin D-3 by synthesis in the skin or from dietary and supplemental sources is essential for bone health throughout life. Vitamin D deficiency is defined as a 25(OH)D concentration < 20 ng/mL (50 nmol/L); vitamin D sufficiency as a 25(OH)D > 30 ng/mL (75 nmol/L), and insufficiency as 21-29 ng/mL. Vitamin D deficiency and insufficiency has been linked to a wide variety of chronic diseases including common cancers, autoimmune, cardiovascular, and infectious diseases. Healthcare professionals need to be aware of the vitamin D deficiency pandemic. Guidelines for sensible sun exposure and supplemental vitamin D of 800-1000 IU/day are needed. (C) 2008 International Life Sciences Institute.