Epidemiology of pterygium in Victoria, Australia

Epidemiology of pterygium in Victoria, Australia
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DOI:
10.1136/bjo.84.3.289
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发表时间:
2000-03-01
影响因子:
4.1
通讯作者:
Taylor, HR
Taylor, HR
中科院分区:
医学2区
文献类型:
--
作者:
McCarty, CA;Fu, CL;Taylor, HR

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目的-描述翼状胬肉在澳大利亚维多利亚州40岁及以上居民的人群样本中的患病率和危险因素。方法-分层包括从墨尔本统计部门随机选择的9个集群,从9个墨尔本集群的5公里半径内的疗养院随机选择的14个疗养院,以及从维多利亚农村随机选择的四个群组。翼状胬肉从顶端到基部中间以毫米为单位测量。在一次采访中,人们被询问有关以前的眼科手术,包括手术切除翼状胬肉,和他们一生中暴露在阳光下。他们的年龄从40岁到101岁不等,其中2850人(55.4%)为女性。墨尔本队列中只有1人报告了既往翼状胬肉手术,7名农村居民报告了既往手术;养老院居民没有这些信息。在3229名接受临床检查的墨尔本居民中,有39名(1.2%)、6名(1.7%)疗养院居民和96名(6.7%)农村居民在临床检查时出现翼状胬肉。人群中的总体加权人群发生率为2.83%(95% CL 2.35,3.31)。翼状胬肉的独立危险因素为年龄(OR=1.23,95% CL=1.06,1.44)、男性(OR=2.02,95% CL=1.35,3.03)、农村居民(OR=5.28,95% CL=3.56,7.84)和终生眼部日晒(OR=1.63,95% CL=1.18,2.25)。日光和翼状胬肉的归因风险为43.6%(95%CL =42.7,44.6)。结果是相同的,当眼睛的UV-B暴露被替换在模型中的宽带sunexposed. Conclusion翼状胬肉是一个重要的公共卫生问题,在农村地区,主要是由于眼睛的阳光照射。
Aim-To describe the prevalence of and risk factors for pterygium in a population based sample of residents of the Australian state of Victoria who were aged 40 years and older.Methods-The strata comprised nine randomly selected clusters from the Melbourne statistical division, 14 nursing homes randomly selected from the nursing homes within a 5 kilometre radius of the nine Melbourne clusters, and four randomly selected clusters from rural Victoria. Pterygium was measured in millimetres from the tip to the middle of the base. During an interview people were queried about previous ocular surgery, including surgical removal of pterygium, and their lifetime exposure to sunlight.Results-5147 people participated. They ranged in age from 40 to 101 years and 2850 (55.4%) were female. Only one person in the Melbourne cohort reported previous pterygium surgery, and seven rural residents reported previous surgery; this information was unavailable for the nursing home residents. Pterygium was present upon clinical examination in 39 (1.2%) of the 3229 Melbourne residents who had the clinical examination, six (1.7%) of the nursing home residents, and 96 (6.7%) of the rural residents. The overall weighted population rate in the population was 2.83% (95% CL 2.35, 3.31). The independent risk factors for pterygium were found to be age (OR=1.23, 95% CL=1.06, 1.44), male sex (OR=2.02, 95% CL=1.35, 3.03), rural residence (OR=5.28, 95% CL=3.56, 7.84), and lifetime ocular sun exposure (OR=1.63, 95% CL=1.18, 2.25). The attributable risk of sunlight and pterygium was 43.6% (95% CL=42.7, 44.6). The result was the same when ocular UV-B exposure was substituted in the model for broad band sun exposure.Conclusion-Pterygium is a significant public health problem in rural areas, primarily as a result of ocular sun exposure.