Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China
Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China
复制标题
上海黄浦江流域抗生素的发生、分布及季节变化
DOI：
10.1016/j.chemosphere.2010.11.028
复制
发表时间：
2011-02-01
期刊：
影响因子：
8.8
通讯作者：
Yu, Zhenyang
中科院分区：
文献类型：
--
作者：
Jiang, Lei;Hu, Xialin;Yu, Zhenyang
于2009年6月和12月在黄浦江沿着的19个采样点采集水样。调查了22种抗生素的出现、分布和季节变化，包括4种四环素类、3种氯霉素类、2种大环内酯类、6种氟喹诺酮类、6种磺胺类和甲氧苄啶类。结果发现，19个采样点均受到抗生素污染。磺胺甲嘧啶、氟哌酸、氟罗沙星和沙拉芬4种抗生素未检出。其余18种抗生素的检出率在5.3 ~ 100%之间。检测到的抗生素的中位浓度范围从定量限到36.71 ng L-1（四环素）在6月和313.44 ng L-1（磺胺二甲嘧啶）在12月。12月检出的抗生素数量和总体抗生素浓度高于6月，这是由于河流流量条件不同。在6月至12月期间，观察到各组抗生素的不同优势抗生素。郊区采样点的四环素类等兽用抗生素总浓度高于市区采样点，表明畜牧业和农业活动是抗生素污染的重要来源。(C)2010爱思唯尔有限公司版权所有。
Water samples were collected from 19 sampling sites along the Huangpu River in June and December 2009. The occurrence, distribution and seasonal variation of 22 antibiotics, including four tetracyclines, three chloramphenicols, two macrolides, six fluoroquinolones, six sulfonamides and trimethoprim were investigated. It was found that all 19 sampling sites were contaminated by antibiotics. Four antibiotics (sulfamerazine, norfloxacin, fleroxacin and sarafloxacin) were not detected. The detection frequencies of the other 18 antibiotics were in the range of 5.3-100%. The median concentrations of the detected antibiotics ranged from quantification limits to 36.71 ng L-1 (tetracycline) in June and to 313.44 ng L-1 (sulfamethazine) in December. The number of detected antibiotics and the overall antibiotic concentrations were higher in December than in June due to the different river flow conditions. Different dominant antibiotics were observed for each group of antibiotics between June and December. Higher total concentrations of veterinary antibiotics such as tetracyclines were observed in suburban sampling sites than in unban sites, indicating the role of livestock and agricultural activities as an important source of antibiotic contamination. (C) 2010 Elsevier Ltd. All rights reserved.