STUDIES ON THE TERMINAL STEPS OF IMMUNE HEMOLYSIS. II. RESOLUTION OF THE E TRANSFORMATION REACTION INTO MULTIPLE STEPS.
STUDIES ON THE TERMINAL STEPS OF IMMUNE HEMOLYSIS. II. RESOLUTION OF THE E TRANSFORMATION REACTION INTO MULTIPLE STEPS.
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免疫溶血最终步骤的研究。
DOI：
10.4049/jimmunol.94.2.295
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发表时间：
1964
影响因子：
4.4
通讯作者：
Tibor Borsos
中科院分区：
文献类型：
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作者：
Michael M. Frank;Herbert J. Rapp;Tibor Borsos
E* 的裂解需要至少三个单独的反应。有证据表明，反应序列中的第一步是温度依赖性的激活，发生在0.09 M乙二胺四乙酸（EDTA）的存在下。活化之后是两个相对不依赖于温度的步骤。其中第一个可以被0.09 M EDTA阻断，第二个可以被25%牛血浆白蛋白阻断。
Lysis of E* requires at least three separate reactions. Evidence is presented that the first step in the sequence of reactions is a temperature-dependent activation that takes place in the presence of 0.09 M ethylenediaminetetracetate (EDTA). The activation is followed by two steps that are relatively temperature-independent. The first of these can be blocked by 0.09 M EDTA, and the second can be blocked by 25% bovine plasma albumin.