Evidence for an ancient whole-genome duplication event in rice and other cereals.
Evidence for an ancient whole-genome duplication event in rice and other cereals.
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发表时间：
2005-05
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通讯作者：
C. Tian;Y. Xiong;Tie-Yan Liu;Shouhong Sun;Liang-biao Chen;Mingsheng Chen
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作者：
C. Tian;Y. Xiong;Tie-Yan Liu;Shouhong Sun;Liang-biao Chen;Mingsheng Chen
基因复制被认为是进化的加速器。古老的基因组复制事件已经在不同的生物体中被鉴定，例如酵母、脊椎动物和拟南芥。在这里，我们已经确定了水稻基因组中的全基因组复制事件（WGD），这发生在大约7000万年前（mya）的禾本科植物分化之前。共检测到117个重复区，分布在水稻全部12条染色体上，约占水稻基因组的60%。这些重复片段上约有20%的基因以重复对的形式保留下来。相比之下，60%的转录因子基因保留为重复。在祖先草基因组中鉴定WGD将影响草基因组进化的研究，并表明多倍化和随后的基因丢失和染色体重排在草的多样化中发挥了重要作用。
Gene duplication has been proposed as an accelerator of evolution. Ancient genome duplication events have been identified in diverse organisms, such as yeast, vertebrates, and Arabidopsis. Here, we have identified a whole genome duplication event (WGD) in the rice genome, which took place prior to the divergence of grasses about 70 million years ago (mya). A total of 117 duplicated blocks were detected, which are distributed on all 12 chromosomes and cover about 60% of the rice genome. About 20% genes on these duplicated segments are retained as duplicate pairs. In contrast, 60% of the transcription factor genes are retained as duplicates. The identification of a WGD in the ancestral grass genome will impact the study of grass genome evolution, and suggest that polyploidization and subsequent gene losses and chromosomal rearrangements have played an important role in the diversification of grasses.