ALOE VERA, HYDROCORTISONE, AND STEROL INFLUENCE ON WOUND TENSILE-STRENGTH AND ANTI-INFLAMMATION
ALOE VERA, HYDROCORTISONE, AND STEROL INFLUENCE ON WOUND TENSILE-STRENGTH AND ANTI-INFLAMMATION
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DOI：
10.7547/87507315-84-12-614
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发表时间：
1994-12-01
影响因子：
0.7
通讯作者：
STEWART, CB
中科院分区：
文献类型：
--
作者：
DAVIS, RH;DIDONATO, JJ;STEWART, CB
使用伤口抗张强度测定，每天以Inn和300 mg/kg剂量的芦荟持续4天阻断乙酸氢化可的松的伤口加热抑制高达100%。这种反应是由于A.维拉掩蔽伤口愈合抑制剂，如甾醇和某些氨基酸。甾醇在减少巴豆油诱导的耳肿胀方面显示出良好的抗炎活性（~ 36%）。该活性显示出剂量-反应关系。
Aloe vera at doses of Inn and 300 mg/kg daily for 4 days blocked the wound heating suppression of hydrocortisone acetate up to 100% using the wound tensile strength assay. This response was because of the growth factors present in A. vera masking the wound healing inhibitors such as sterols and certain amino acids. The sterols showed good anti-inflammatory activity (-36%) in reducing the croton oil-induced ear swelling. This activity displayed a dose-response relationship.