Food Cues and Obesity: Overpowering Hormones and Energy Balance Regulation
Food Cues and Obesity: Overpowering Hormones and Energy Balance Regulation
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DOI：
10.1007/s13679-018-0303-1
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发表时间：
2018-06-01
影响因子：
8.8
通讯作者：
Seo, Dongju
中科院分区：
文献类型：
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作者：
Belfort-DeAguiar, Renata;Seo, Dongju
综述目的在现代肥胖环境中，食物线索通过破坏激素和能量平衡机制在肥胖的发展中起着至关重要的作用。因此，在普遍存在的食物线索的背景下，了解进食行为和肥胖的神经生物学是至关重要的。本文综述了生理学的喂养，激素调节能量平衡，和食物线索的反应，并讨论了他们的贡献obesity.Recent Findings食物线索对人体生理有很大的影响。肥胖个体改变了大脑和外周的食物线索引发的反应，压倒了激素和能量平衡调节。食物线索暴露过程中的稳态破坏导致持续的食物摄入，不成功的体重管理和不良的治疗结果，这进一步促进了肥胖的流行。综述的结果强调了食物线索在肥胖流行中的关键作用，这需要多方面的方法来预防和治疗肥胖，包括心理社会干预，以减少食物线索反应，沿着常规治疗。
Purpose of Review In the modern obesogenic environment, food cues play a crucial role in the development of obesity by disrupting hormone and energy balance mechanisms. Thus, it is critical to understand the neurobiology of feeding behaviors and obesity in the context of ubiquitous food cues. The current paper reviews the physiology of feeding, hormonal regulation of energy balance, and food cue responses and discusses their contributions to obesity.Recent Findings Food cues have strong impact on human physiology. Obese individuals have altered food cue-elicited responses in the brain and periphery, overpowering hormone and energy balance regulation. Disrupted homeostasis during food cue exposure leads to continued food intake, unsuccessful weight management, and poor treatment outcomes, which further contributes to obesity epidemic.Summary Findings from the review emphasize the crucial role of food cues in obesity epidemic, which necessitates multidimensional approaches to the prevention and treatment of obesity, including psychosocial interventions to reduce food cue reactivity, along with conventional treatment.