Indium(III) Chloride-Catalyzed Isocyanide Insertion Reaction to Construct Complex Spirooxindole.
Indium(III) Chloride-Catalyzed Isocyanide Insertion Reaction to Construct Complex Spirooxindole.
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DOI：
10.1021/acs.orglett.5b02432
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发表时间：
2015-09
期刊：
影响因子：
5.2
通讯作者：
Ya‐Ming Tian;Lumin Tian;Xiang He;Chunju Li;X. Jia;Jian Li
中科院分区：
文献类型：
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作者：
Ya‐Ming Tian;Lumin Tian;Xiang He;Chunju Li;X. Jia;Jian Li
已经公开了使用氯化铟（III）作为催化剂与亚甲基吲哚啉酮的不寻常的多异氰化物插入反应。该策略允许以有效的方式快速构建结构复杂的螺羟吲哚。该方法具有反应条件温和、原子经济、底物范围广等特点。
An unusual multiple isocyanide insertion reaction with methyleneindolinone using indium(III) chloride as the catalyst has been disclosed. This strategy allows for the rapid construction of structurally complex spirooxindole in an efficient manner. The present protocol features mild conditions, atom economy, and broad substrate scope.