Tolerance of efavirenz in children
Tolerance of efavirenz in children
复制标题
儿童依非韦伦耐受性
DOI：
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复制
发表时间：
2001
期刊：
影响因子：
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通讯作者：
S. Blanche
中科院分区：
文献类型：
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作者：
J. Teglas;P. Quartier;J. Treluyer;M. Burgard;V. Grégoire;S. Blanche
ObjectiveTo extend the limited knowledge of efavirenz tolerance in children. MethodAn observational study of 33 children given efavirenz combined with various others agents and followed in a single institution. ResultsFifteen (42%) of the children presented at least one clinically discernable side effect, cutaneous (n = 5), nervous system (n = 10), or both (n = 2). Intolerance led to treatment interruption in seven children but the main symptom was transitory dizziness or other signs similar to those observed in adults. ConclusionEarly, often transient nervous system side effects require careful preparation with the child and his family to avoid premature and inadequate withdrawal from treatment.
