Using the Framingham model to predict heart disease in the United Kingdom: retrospective study
Using the Framingham model to predict heart disease in the United Kingdom: retrospective study
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DOI：
10.1136/bmj.320.7236.676
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发表时间：
2000-03-11
影响因子：
--
通讯作者：
Neary, RH
中科院分区：
文献类型：
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作者：
Ramachandran, S;French, JM;Neary, RH
关于使用药物降低血清脂质浓度以预防冠心病的指南，针对患有该疾病绝对风险较高的患者进行治疗。尽管可以使用风险表1（例如谢菲尔德表）得出患者患心脏病的绝对风险，但这些风险表基于弗雷明汉模型，可能不适用于英国人群。 2 我们的目的是确定弗雷明汉模型是否能够准确预测英国白人男性和女性患冠心病的风险。
Guidelines on the use of drugs to lower serum concentrations of lipids to prevent coronary heart disease target treatment to patients who have a high absolute risk of the disease. Although a patient’s absolute risk of heart disease can be derived using risk tables1—for example, the Sheffield table—these are based on the Framingham model which may not be applicable to the population in the United Kingdom. 2 We aimed to determine whether the Framingham model accurately predicts the risk of coronary heart disease among white men and women in the United Kingdom.