The relationship between previous fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection
The relationship between previous fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection
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DOI：
10.1086/510074
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发表时间：
2007-01-15
影响因子：
11.8
通讯作者：
McMahon, Brian J.
中科院分区：
文献类型：
--
作者：
Carothers, John J.;Bruce, Michael G.;McMahon, Brian J.
幽门螺杆菌感染患者既往使用氟喹诺酮类药物与左氧氟沙星耐药性之间的关系尚不清楚。在125例入组患者中，8.8%的幽门螺杆菌分离株对左氧氟沙星耐药。左氧氟沙星耐药与过去10年氟喹诺酮类药物的使用以及氟喹诺酮类药物的总疗程有关（P < 0.001）。
The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H. pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P < .001).