Cancer in US air force veterans of the Vietnam war
Cancer in US air force veterans of the Vietnam war
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DOI：
10.1097/01.jom.0000111603.84316.0f
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发表时间：
2004-02-01
影响因子：
3.2
通讯作者：
Michalek, JE
中科院分区：
文献类型：
--
作者：
Akhtar, FZ;Garabrant, DH;Michalek, JE
总结了越战空军退伍军人的癌症发病率和死亡率。指标对象为在越南喷洒2,3,7,8四氯二苯并对二恶英（二恶英）污染除草剂的牧场之手行动退伍军人。同一时期在东南亚进行了比较，但没有喷洒除草剂。我们利用国家发病率和死亡率评估了癌症发病率和死亡率，并对比了三种牧场手二恶英暴露类别的癌症风险。与全国相比，白人牧场老兵患黑色素瘤和前列腺癌的几率有所增加。在东南亚生活最多2年的退伍军人中，任何部位的癌症风险，前列腺癌和黑色素瘤的风险在二恶英暴露最高的类别中都有所增加。这些结果似乎与癌症与接触二恶英之间的联系一致。
Cancer incidence and mortality were summarized in Air Force veterans of the Vietnam War. The index subjects were Operation Ranch Hand veterans who sprayed 2,3,7,8 tetrachlorodibenzo-p-dioxin (dioxin)-contaminated herbicides in Vietnam. Comparisons served in Southeast Asia during the same period but did not spray herbicides. We assessed cancer incidence and mortality using national rates and contrasted cancer risk in each of three Ranch Hand dioxin exposure categories relative to comparisons. The incidence of melanoma and prostate cancer was increased among white Ranch Hand veterans relative to national rates. Among veterans who spent at most 2 years in Southeast Asia, the risk of cancer at any site, of prostate cancer and of melanoma was increased in the highest dioxin exposure category. These results appear consistent with an association between cancer and dioxin exposure.