Umbilical cord clamping and skin-to-skin contact in deliveries from women positive for SARS-CoV-2: a prospective observational study
Umbilical cord clamping and skin-to-skin contact in deliveries from women positive for SARS-CoV-2: a prospective observational study
复制标题
DOI：
10.1111/1471-0528.16597
复制
发表时间：
2020-11-30
影响因子：
5.8
通讯作者：
Martinez Perez, O.
中科院分区：
文献类型：
--
作者：
Mejia Jimenez, I;Salvador Lopez, R.;Martinez Perez, O.
目的探讨延迟性脐带钳夹术（DCC）对确诊为SARS-CoV-2感染的孕妇的安全性。设计、设置和参与者前瞻性观察研究，包括2020年3月1日至5月31日期间403名SARS-CoV-2孕妇的流行病学信息。数据收集自参与西班牙COVID-19登记的70个中心。方法患者的信息从他们的病历中收集。主要结局和指标SARS-CoV-2的围产期传播率和产后14天内新生儿感染的发展。结果早期脐带钳夹（ECC）组包括231名婴儿DCC组172例（42.7%）。在产后12小时内进行的鼻咽PCR检测确定了5例阳性新生儿（占总检测数的1.7%），其中2例来自ECC组（1.7%），3例来自DCC组（3.6%）。两组新生儿SARS-CoV-2检测结果无显著差异。没有发现垂直传播的确诊病例。在分娩后的前24小时内进行皮肤接触的母亲比例在DCC组中显着较高（84.3%对45.9%）。DCC组在产后立即进行母乳喂养的比例也明显较高（77.3%对50.2%）。结论我们的研究结果显示，在进行ECC或DCC，皮肤接触或母乳喂养时，围产期结局没有差异。
Objective To demonstrate that delayed cord clamping (DCC) is safe in mothers with confirmed SARS-CoV-2 infection.Design, setting and participants Prospective observational study involving epidemiological information from 403 pregnant women with SARS-CoV-2 between 1 March and 31 May 2020. Data were collected from 70 centres that participate in the Spanish Registry of COVID-19.Methods Patients' information was collected from their medical chart.Main outcomes and measures The rate of perinatal transmission of SARS-CoV-2 and development of the infection in neonates within 14 days postpartum.Results The early cord clamping (ECC) group consisted of 231 infants (57.3%) and the DCC group consisted of 172 infants (42.7%). Five positive newborns (1.7% of total tests performed) were identified with the nasopharyngeal PCR tests performed in the first 12 hours postpartum, two from the ECC group (1.7%) and three from the DCC group (3.6%). No significant differences between groups were found regarding neonatal tests for SARS-CoV-2. No confirmed cases of vertical transmission were detected. The percentage of mothers who made skin-to-skin contact within the first 24 hours after delivery was significantly higher in the DCC group (84.3% versus 45.9%). Breastfeeding in the immediate postpartum period was also significantly higher in the DCC group (77.3% versus 50.2%).Conclusions The results of our study show no differences in perinatal outcomes when performing ECC or DCC, and skin-to-skin contact, or breastfeeding.Tweetable abstract This study demonstrates that delayed cord clamping is safe in mothers with confirmed SARS-CoV-2 infection.