The cerebellum: Its role in language and related cognitive and affective functions
The cerebellum: Its role in language and related cognitive and affective functions
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DOI：
10.1016/j.bandl.2012.11.001
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发表时间：
2013-12-01
影响因子：
2.5
通讯作者：
Marien, Peter
中科院分区：
文献类型：
--
作者：
De Smet, Hyo Jung;Paquier, Philippe;Marien, Peter
在过去的几十年里，关于小脑是运动功能的唯一协调者的传统观点已经得到了实质性的重新定义。神经解剖学、神经影像学和临床研究已将小脑的作用扩展到认知和情感加工的调节。神经解剖学研究表明，小脑与幕上关联区的连接涉及较高的认知和情感功能，而功能神经成像和临床研究则提供了小脑参与各种认知和情感任务的证据。本文综述了最近公认的小脑在语言及相关的认知和行为-情感功能中的作用。此外，还将简要讨论典型的小脑综合征，如小脑认知情感综合征(CCAS)和后颅窝综合征(PFS)，并对目前关于小脑语言、认知和情感调节作用的神经生物学机制的假设进行综述。(C)2012 Elsevier Inc.保留所有权利。
The traditional view on the cerebellum as the sole coordinator of motor function has been substantially redefined during the past decades. Neuroanatomical, neuroimaging and clinical studies have extended the role of the cerebellum to the modulation of cognitive and affective processing. Neuroanatomical studies have demonstrated cerebellar connectivity with the supratentorial association areas involved in higher cognitive and affective functioning, while functional neuroimaging and clinical studies have provided evidence of cerebellar involvement in a variety of cognitive and affective tasks. This paper reviews the recently acknowledged role of the cerebellum in linguistic and related cognitive and behavioral-affective functions. In addition, typical cerebellar syndromes such as the cerebellar cognitive affective syndrome (CCAS) and the posterior fosa syndrome (PFS) will be briefly discussed and the current hypotheses dealing with the presumed neurobiological mechanisms underlying the linguistic, cognitive and affective modulatory role of the cerebellum will be reviewed. (C) 2012 Elsevier Inc. All rights reserved.