Effects of ultrasound modes on mandibular osteodistraction
Effects of ultrasound modes on mandibular osteodistraction
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DOI：
10.1177/154405910808701018
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发表时间：
2008-10-01
影响因子：
7.6
通讯作者：
Royston, T. J.
中科院分区：
文献类型：
--
作者：
El-Bialy, T. H.;Elgazzar, R. F.;Royston, T. J.
既往研究表明，治疗性脉冲超声（pulsed）对骨折愈合的刺激作用优于连续超声（continuous）。我们的预测假设是脉冲超声在下颌骨牵张术中比连续超声能产生更好的骨形成。将36只新西兰兔分为3组，每组12只。骨牵张术以3mm /天的速度进行，连续5天。组1为脉冲超声，组2为连续超声，组3为对照组（仅牵张）。通过定量骨密度（QBD）、力学测试和组织学检查评估骨形成。牵张后前2周，2组骨形成明显增强（p < 0.05）；第3、4周时，组1骨形成量明显高于组2 （p < 0.05）。早期阶段的骨愈合更多地通过连续，而晚期阶段的骨愈合更多地通过脉冲，超声。缩写：脉冲，低强度脉冲超声；连续，低强度连续超声。
Previous studies have shown that therapeutic pulsed ultrasound (pulsed) has superior stimulatory effect on bone fracture healing compared with continuous ultrasound (continuous). Our predictive hypothesis was that pulsed ultrasound can produce better bone formation during mandibular osteodistraction than continuous ultrasound. Thirty-six New Zealand rabbits were divided into 3 groups of 12. Osteodistraction was performed at 3 mm/day for 5 days. Group 1 received pulsed, group 2 received continuous ultrasound, and group 3 was the control group (distraction only). Bone formation was assessed by quantitative bone density (QBD), mechanical testing, and histological examination. In the first 2 wks post-distraction, group 2 showed enhanced bone formation more than group 1 (p < 0.05); however, in the 3rd and 4th wks, group 1 showed more bone formation than group 2 (p < 0.05). Earlier stages of bone healing were enhanced more by continuous, whereas late stages were enhanced more by pulsed, ultrasound. Abbreviations: PULSED, low-intensity pulsed ultrasound; CONTINUOUS, lowintensity continuous ultrasound.