Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma
Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma
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DOI：
10.1038/ng1277
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发表时间：
2004-01-01
期刊：
影响因子：
30.8
通讯作者：
Namba, S
中科院分区：
文献类型：
--
作者：
Oshima, K;Kakizawa, S;Namba, S
长期以来，人们一直在寻找生命所必需的最小基因组。我们报告了专性细胞内植物病原体植原体（Candidatus Phytoplasma asteris，OY 菌株）的 860 kb 基因组。植原体基因组编码的代谢功能比支原体基因组还要少。它缺乏戊糖磷酸循环，更令人意外的是，缺乏被认为对生命至关重要的 ATP 合酶亚基。这可能是还原进化的结果，是作为营养丰富的环境中的细胞内寄生虫的生命的结果。
The minimal gene set essential for life has long been sought. We report the 860-kb genome of the obligate intracellular plant pathogen phytoplasma (Candidatus Phytoplasma asteris, OY strain). The phytoplasma genome encodes even fewer metabolic functions than do mycoplasma genomes. It lacks the pentose phosphate cycle and, more unexpectedly, ATP-synthase subunits, which are thought to be essential for life. This may be the result of reductive evolution as a consequence of life as an intracellular parasite in a nutrient-rich environment.