EXCITABILITY AND INHIBITIBILITY OF MOTONEURONS OF DIFFERENT SIZES
EXCITABILITY AND INHIBITIBILITY OF MOTONEURONS OF DIFFERENT SIZES
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DOI：
10.1152/jn.1965.28.3.599
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发表时间：
1965-01-01
影响因子：
2.5
通讯作者：
CARPENTER, DO
中科院分区：
文献类型：
--
作者：
HENNEMAN, E;SOMJEN, G;CARPENTER, DO
在去大脑猫上研究了不同大小的运动神经元对各种类型的反射兴奋和抑制的敏感性。从腹根细丝记录的冲动的幅度作为轴突直径和相对细胞大小的指标。细胞被募集或沉默的顺序被认为是它们相对兴奋性或“抑制性”的指数。“一般来说，无论用于比较的反射通路如何，灯丝中任何2个响应单元中较小的单元在刺激强度较低时放电，而不是较大的单元。此外，单位越大，越容易受到抑制，无论抑制是“直接的”，内部介导的，自生的或复发。从总共700多对单位，以各种方式进行比较，得出的结论是，运动神经元的兴奋性是其细胞大小的反函数，其“抑制性”是细胞大小的直接函数。
The susceptibility of motor neurons of different sizes to various types of reflex excitation and inhibition was investigated in decerebrate cats. The amplitude of impulses recorded from ventral root filaments was taken as an index of axonal diameter and relative cell size. The order in which cells were recruited or silenced was regarded as an index of their relative excitabilities or "inhibitibilities." In general, the smaller of any 2 responding units in a filament was discharged at a lower intensity of stimulation than the larger regardless of the reflex pathway used for the comparison. Moreover, the larger a unit was, the more susceptible it was to inhibition, regardless of whether the inhibition was "direct," internuncially mediated, autogenetic or recurrent. From a total of more than 700 pairs of units, compared in various ways, it was concluded that the excitability of motor neurons is an inverse function of their cell size and that their "inhibitibility" is a direct function of cell size.