Serological observations on the epidemiology of parvovirus enteritis of dogs.
Serological observations on the epidemiology of parvovirus enteritis of dogs.
复制标题
犬细小病毒性肠炎流行病学的血清学观察。
DOI：
10.1111/j.1751-0813.1980.tb05661.x
复制
发表时间：
1980
影响因子：
1.1
通讯作者：
R. H. Johnson
中科院分区：
文献类型：
--
作者：
J. Smith;T. S. Farmer;R. H. Johnson
本文应用微量血凝抑制试验（HI）对507份犬血清进行了检测，其中119份为犬细小病毒性肠炎（CPE）临床病例。在一只幼犬呈阳性的犬舍中，所有2岁以下接触犬的血清均呈阳性，但年龄较大的犬的血清通常呈阴性。CPE通常是小于6月龄的犬的疾病。在CPE发生后数小时内HI滴度较高，HI应答先于临床体征至少24小时。免疫母犬的幼犬获得了被动免疫;正因为如此，疾病的发病率和严重程度似乎会下降。HI滴度峰值出现在患病的第一周，有时达到131000。
Using microtitre haemagglutination-inhibition (HI) test, the authors examined serum samples from 507 dogs, 119 of which were clinical cases of canine parvovirus enteritis (CPE). In kennels where one pup was positive, sera from all in-contact dogs under 2 years old were positive, but sera from older dogs were generally negative. CPE was generally a disease of dogs less than 6-months-old. The HI titre was high within a few hours of onset of CPE, and the HI response preceded clinical signs by at least 24 hours. Puppies from immune dams acquired passive immunity; because of this, it seems likely that incidence and severity of the disease will fall. Peak HI titres occurred during the first week of illness, sometimes reaching 131 000.