Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.
Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.
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新型抗叶酸剂 N10-propargyl-5,8-dideazafolate 及其聚谷氨酸盐对人二氢叶酸还原酶、人胸苷酸合成酶和含有不同水平二氢叶酸还原酶的 KB 细胞的活性。
作者：
Cheng,YC;Dutschman,GE;Starnes,MC;Fisher,MH;Nanavathi,NT;Nair,MG
