Short- and Long-Term Outcomes for Extremely Preterm Infants.

Short- and Long-Term Outcomes for Extremely Preterm Infants.
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DOI:
10.1055/s-0035-1571202
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发表时间:
2016-02
影响因子:
2
通讯作者:
Patel RM
Patel RM
中科院分区:
医学4区
文献类型:
--
作者:
Patel RM

文献摘要

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早产是全球婴儿死亡的主要原因。在发达国家,极早产儿对新生儿和婴儿死亡率的贡献不成比例。近年来,这一高危人群的存活率逐步提高。尽管有这些改进,大约每4名极早产儿中就有1人在分娩住院期间死亡。在那些幸存下来的人中,呼吸系统和其他疾病很常见,尽管它们对生活质量的影响是不同的。此外,长期的神经发育障碍是患者、临床医生和家庭的一大担忧。然而,多种因素的相互作用导致了神经发育障碍,随着时间的推移,测量方法会发生变化,结果可能很难定义和预测。了解极早产儿的结局可以帮助更好地向家庭提供产前和产后护理方面的咨询,并指导提高存活率而不发生发病率的策略。这篇综述总结了最近的证据,以提供对极早产儿的短期和长期结果的概述。
Prematurity is the leading cause of infant mortality worldwide. In developed countries, extremely preterm infants contribute disproportionately to both neonatal and infant mortality. Survival of this high-risk population has incrementally improved in recent years. Despite these improvements, approximately 1 in 4 extremely preterm infants dies during the birth hospitalization. Among those who survive, respiratory and other morbidities are common, although their effect on quality of life is variable. In addition, long-term neurodevelopmental impairment is a large concern for patients, clinicians and families. However, the interplay of multiple factors contribute to neurodevelopmental impairment, with measures that change over time and outcomes that can be difficult to define and predict. Understanding outcomes of extremely preterm infants can help better counsel families regarding antenatal and postnatal care and guide strategies to improve survival without morbidity. This review summarizes recent evidence to provide an overview into the short- and long-term outcomes for extremely preterm infants.