Cellular aspects of wound healing
Cellular aspects of wound healing
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DOI：
10.1590/s0365-05962009000300007
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发表时间：
2009-07-01
影响因子：
1.7
通讯作者：
Coutinho-Netto, Joaquim
中科院分区：
文献类型：
--
作者：
Mendonça, Ricardo José de;Coutinho-Netto, Joaquim
伤口愈合是一个动态的相互作用的过程，涉及一系列的分子和细胞事件。细胞和分子生物学的最新进展极大地扩展了我们对创伤修复和组织再生所涉及的生物学过程的理解。从血浆外渗、凝血和血小板聚集到损伤组织的上皮再生和重塑，生物体通过试图恢复功能性组织而起作用。因此，本研究包括涉及伤口愈合过程的几个细胞方面，以及用于治疗与伤口愈合并发症相关的病理学的主要药物。经济方面也得到了解决，主要涉及糖尿病足的慢性伤口。
Wound healing is a dynamic interactive process that involves a sequence of molecular and cellular events. Recent advances in cellular and molecular biology have greatly expanded our understanding of the biological process involved in wound repair and tissue regeneration. From plasma extravasation, with coagulation and platelet aggregation, to reepithelialization and remodeling of injured tissue, the organism acts by trying to restore functionality tissue. Thus, the present study encompasses several cellular aspects involved in the wound healing process, as well as the main drugs used in treating the pathology related to wound healing complications. Economic aspects are also addressed, mainly related to chronic wounds of diabetic feet.