Reversal of sleep apnea hypopnea syndrome in end-stage renal disease after kidney transplantation
Reversal of sleep apnea hypopnea syndrome in end-stage renal disease after kidney transplantation
复制标题
DOI：
10.1016/s0272-6386(99)70401-4
复制
发表时间：
1999-10-01
影响因子：
13.2
通讯作者：
Brown, LK
中科院分区：
文献类型：
--
作者：
Auckley, DH;Schmidt-Nowara, W;Brown, LK
睡眠呼吸暂停低通气综合征（SAHS）在终末期肾病（ESRD）患者中非常常见，尽管这两种疾病的潜在机制仍有待更好地定义，但可能涉及多种因素。我们报告一个人与终末期肾病与严重的SANS解决后，肾移植。SANS的改善与ESRD的有效治疗并行，这表明发病机制涉及不稳定的呼吸模式，可能由代谢状态改变、尿毒症和容量状态变化引起。还讨论了细胞因子水平升高的可能性，值得进一步关注。(C)1999年由国家肾脏基金会，公司。
Sleep apnea hypopnea syndrome (SAHS) is extremely common in patients with end-stage renal disease (ESRD), Although the underlying mechanisms linking these 2 conditions remain to be better defined, it is likely that multiple factors are involved. We report an individual with ESRD with severe SANS that resolved after kidney transplantation. The improvement in SANS paralleling the effective treatment of ESRD suggests the pathogenesis involves an unstable breathing pattern, possibly caused by an altered metabolic state, uremia, and changes in volume status, The possibility that elevations in cytokine levels could be involved also is discussed and deserves further attention. (C) 1999 by the National Kidney Foundation, Inc.