Corneal thickness changes during herpes simplex virus disciform keratitis.
Corneal thickness changes during herpes simplex virus disciform keratitis.
复制标题
单纯疱疹病毒盘状角膜炎期间角膜厚度发生变化。
DOI：
10.1097/00003226-200403000-00008
复制
发表时间：
2004
期刊：
影响因子：
2.8
通讯作者：
Stulting,RDoyle
中科院分区：
文献类型：
--
作者：
Wilhelmus,KirkR;Sugar,Joel;Hyndiuk,RobertA;Stulting,RDoyle
目的探讨单纯疱疹病毒盘状角膜水肿随访期间超声测厚法测定角膜厚度的变化。方法对35例疱疹性角膜炎患者进行裂隙灯生物显微镜检查和超声厚度测量。在随访期间和临床解决角膜炎症的测量与初始角膜厚度进行比较。结果随访期间盘状间质性角膜炎的角膜厚度下降了15%(95%可信区间为10% ~ 20%)，其中65%（95%可信区间为43% ~ 88%）的下降发生在前2周。角膜厚测法测量的角膜中央厚度增加与角膜水肿的生物显微镜检测相关（P= 0.03）
ObjectiveTo describe the changes in corneal thickness determined by ultrasonic pachymetry during follow-up of herpes simplex virus disciform corneal edema.MethodsThirty-five patients with herpetic keratitis underwent slit-lamp biomicroscopy and ultrasonic pachymetry. Measurements during follow-up and at clinical resolution of corneal inflammation were compared with the initial corneal thickness.ResultsCorneal thickness of disciform stromal keratitis decreased 15%(95% confidence interval 10% to 20%) during follow-up, and 65%(95% confidence interval 43% to 88%) of this decrease occurred during the first 2 weeks. Increased central corneal thickness measured by pachymetry was associated with biomicroscopic detection of corneal edema (P= 0.03).Conclusions