Unusual Transcription Regulation of the niaD Gene under Anaerobic Conditions Supporting Fungal Ammonia Fermentation
Unusual Transcription Regulation of the niaD Gene under Anaerobic Conditions Supporting Fungal Ammonia Fermentation
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DOI：
10.1271/bbb.68.978
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发表时间：
2004-01
期刊：
影响因子：
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通讯作者：
Kazuto Takasaki;H. Shoun;A. Nakamura;T. Hoshino;N. Takaya
中科院分区：
文献类型：
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作者：
Kazuto Takasaki;H. Shoun;A. Nakamura;T. Hoshino;N. Takaya
真菌构巢曲霉的niaD基因编码同化硝酸还原酶，外源铵抑制其表达。在缺氧条件下，A.即使在铵存在下，nidulans也表达niaD，并将该基因产物用于异化硝酸盐还原（氨发酵）。这种厌氧条件下的转录调控机制是该菌发酵产氨的关键。
The niaD gene of the fungus Aspergillus nidulans encodes an assimilatory nitrate reductase and exogenous ammonium represses its expression. Under anoxic conditions, however, A. nidulans expressed niaD even in the presence of ammonium and used the gene product for dissimilatory nitrate reduction (ammonia fermentation). This transcription regulation mechanism under anaerobiosis is critical for the fungus to ferment ammonium.