Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial
Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial
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DOI：
10.1136/ard.2010.142018
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发表时间：
2011-10-01
影响因子：
27.4
通讯作者：
Christensen, Robin
中科院分区：
文献类型：
--
作者：
Bliddal, Henning;Leeds, Anthony R.;Christensen, Robin
目的评估1年的症状改善与膝骨关节炎（OA）的肥胖患者在密集的低能量饮食（LED）保持频繁的咨询与营养师相比，最小的attention.Methods的LED程序包括饮食咨询和两个时期的低热量饮食810千卡/天，在第0-8周和第32-36周的组治疗。对照组仅在基线、第8、32、36和52周接受2 h的饮食指导和关注。主要终点（总的西安大略和麦克马斯特大学（WOMAC）指数）进行了评估的平均组差异期间和1 year.Results研究人群包括89例患者，89%的女性，平均年龄63岁。1年后，LED组的平均体重减轻为-10.9 kg（11%），而对照组为-3.6 kg（4%）（p
Objective To evaluate 1-year symptomatic improvement in obese patients with knee osteoarthritis (OA) on an intensive low-energy diet (LED) maintained by frequent consultations with a dietician compared to minimal attention.Methods The LED programme consisted of group therapy with dietary consultations and two periods of a low-calorie diet of 810 kcal/day during weeks 0-8 and weeks 32-36. The control group only received dietary instruction and attention for 2 h at baseline, and at weeks 8, 32, 36 and 52. The primary end point (total Western Ontario and McMaster Universities (WOMAC) index) was assessed as the mean group difference during and after 1 year.Results The study population consisted of 89 patients, 89% women, average age 63 years. After 1 year, mean weight loss in the LED group was - 10.9 kg (11%) versus - 3.6 kg (4%) in the control group (p