Reproductive risk factors, Doppler findings, and outcome of affected births in placental abruption: a population-based analysis.
Reproductive risk factors, Doppler findings, and outcome of affected births in placental abruption: a population-based analysis.
复制标题
生殖危险因素、多普勒检查结果以及胎盘早剥中受影响的分娩结果：基于人群的分析。
DOI：
10.1055/s-2002-36868
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发表时间：
2002
影响因子：
2
通讯作者：
S. Saarikoski
中科院分区：
文献类型：
--
作者：
S. Toivonen;S. Heinonen;M. Anttila;V. Kosma;S. Saarikoski
胎盘早剥约占所有单胎妊娠的1%，本研究的目的是评估与胎盘早剥相关的孕产妇生殖风险因素，以及受影响分娩的结局。我们分析了170名妇女与单胎妊娠并发胎盘剥离谁生在库奥皮奥大学医院从1989年3月至1999年12月。选择普通产科人群（n = 22，905）作为参照组，采用logistic回归分析确定独立的生殖风险因素。同时记录两组患者的多普勒超声检查结果和妊娠结局指标。转诊地区胎盘早剥发生率为0.57%。先兆子痫、大多产、脐带插入、吸烟、胎儿死亡史、高龄产妇（>35岁）和既往流产史是胎盘早剥的独立危险因素，校正后的相对危险度分别为4.39、3.60、2.53、2.46、2.02、1.62和1.55。大多数胎盘早剥发生在低风险妊娠的分娩开始之前，并且就母体生殖风险因素而言是不可预测的。目前产前检测子宫胎盘问题的方法，包括多普勒超声检查，在产前预测胎盘脱垂方面并不有效。受影响的分娩结果仍然很差。
Placental abruption complicates about 1% of all singleton pregnancies and the aim of this study is to assess the reproductive maternal risk factors associated with placental abruption, and the outcome of affected births. We analyze 170 women with singleton pregnancies complicated by placental abruption who gave birth at Kuopio University Hospital from March 1989 to December 1999. The general obstetric population ( n = 22,905) was selected as the reference group and logistic regression analysis was used to identify independent reproductive risk factors. Furthermore, Doppler ultrasonographic results and pregnancy outcome measures in the two groups were also recorded. The incidence of placental abruption was 0.57% in the referral area. Preeclampsia, grand multiparity, velamentous umbilical cord insertion, cigarette smoking, prior fetal demise, advanced maternal age (>35 years), and previous miscarriage were independent risk factors of placental abruption, with adjusted relative risks of 4.39, 3.60, 2.53, 2.46, 2.02, 1.62, and 1.55, respectively. Most cases of placental abruption occur before the onset of labor in low-risk pregnancies and are not predictable with regard to maternal reproductive risk factors. Current antepartum methods of detecting uteroplacental problems, including Doppler ultrasonography, are not effective in prenatal prediction of placental abruption. The outcome of affected births is still poor.