Amusia results in abnormal brain activity following inappropriate intonation during speech comprehension.

Amusia results in abnormal brain activity following inappropriate intonation during speech comprehension.
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DOI:
10.1371/journal.pone.0041411
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Yang Y
Yang Y
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Jiang C;Hamm JP;Lim VK;Kirk IJ;Chen X;Yang Y

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音高处理是人类音调音乐体验所依赖的一项关键能力,对语音韵律的解码也至关重要。先天性失音症是指在正确处理音高的能力上的缺陷,最近的证据表明,这种音高障碍可能会影响语音的处理。在这里,我们提出了第一个电生理证据,证明说普通话的失音症患者在语音理解任务中对韵律的适当或不适当分类受到损害。当出现不适当的韵律刺激时,对照参与者的P600比适当条件下的大,N100比适当条件下的小。相比之下,音乐在适当和不适当的条件下在N100或P600组件中没有显着差异。这进一步证明,与失音症相关的音高感知缺陷也可能影响那些使用声调语言(如普通话)的人在语音理解过程中的语调处理,并表明音乐和语言共享一些认知和神经资源。
Pitch processing is a critical ability on which humans’ tonal musical experience depends, and which is also of paramount importance for decoding prosody in speech. Congenital amusia refers to deficits in the ability to properly process musical pitch, and recent evidence has suggested that this musical pitch disorder may impact upon the processing of speech sounds. Here we present the first electrophysiological evidence demonstrating that individuals with amusia who speak Mandarin Chinese are impaired in classifying prosody as appropriate or inappropriate during a speech comprehension task. When presented with inappropriate prosody stimuli, control participants elicited a larger P600 and smaller N100 relative to the appropriate condition. In contrast, amusics did not show significant differences between the appropriate and inappropriate conditions in either the N100 or the P600 component. This provides further evidence that the pitch perception deficits associated with amusia may also affect intonation processing during speech comprehension in those who speak a tonal language such as Mandarin, and suggests music and language share some cognitive and neural resources.
DOI: 10.1080/01690969308407585
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