Effects of parkinsonism on health status in welding exposed workers
Effects of parkinsonism on health status in welding exposed workers
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DOI：
10.1016/j.parkreldis.2011.05.021
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发表时间：
2011-11-01
影响因子：
4.1
通讯作者：
Racette, Brad A.
中科院分区：
文献类型：
--
作者：
Harris, Rachel C.;Lundin, Jessica I.;Racette, Brad A.
背景：以往的研究表明，焊工经常表现出帕金森病的迹象，如运动迟缓和震颤。证明这些帕金森病的研究结果与生活质量（QoL）或健康状况的下降可能有重要的影响工人的安全和performance.Methods：主题包括394活跃的工人暴露于焊接烟雾和评估帕金森病的运动障碍专家在一个工作场所为基础的流行病学研究。如果统一帕金森病评定量表运动子部分第3部分（UMRS 3）评分>= 15，则受试者被诊断为帕金森综合征。所有受试者完成了帕金森氏病（PD）症状问卷和PDQ39，广泛使用的生活质量和健康状况测量PD.Results：总PDQ39评分和所有分项评分是更大的焊工帕金森症比焊工没有帕金森症，观察到的流动性，情绪健康，和日常生活活动（ADL）的最显着差异。焊接暴露工人与帕金森病的PDQ39评分是相似的分数看到在一组早期PD patients.Conclusion：帕金森病在积极的，焊接暴露工人的健康状况和生活质量的减少影响范围广泛的类别和范围内看到早期PD。(C)2011爱思唯尔有限公司版权所有。
Background: Previous studies suggest that welders frequently display parkinsonian signs, such as bradykinesia and tremor. Demonstrating that these parkinsonian findings are associated with reductions in quality of life (QoL) or health status could have important repercussions for worker safety and performance.Methods: Subjects included 394 active workers exposed to welding fumes and evaluated for parkinsonism by movement disorders experts in a worksite-based epidemiology study. Subjects were diagnosed with parkinsonism if the Unified Parkinson Disease Rating Scale motor subsection part 3 (UPDRS3) score was >= 15. All subjects completed a Parkinson's disease (PD) symptom questionnaire and the PDQ39, a widely used QoL and health status measure for PD.Results: Total PDQ39 score and all subscores were greater in welders with parkinsonism than welders without parkinsonism, with the most significant differences observed for mobility, emotional well-being, and activities of daily living (ADL's). The PDQ39 scores for welding exposed workers with parkinsonism were similar to scores seen in a group of early PD patients.Conclusion: Parkinsonism in active, welding exposed workers is associated with reductions in health status and QoL affecting a broad range of categories and within the range seen in early PD. (C) 2011 Elsevier Ltd. All rights reserved.