Development of a Tailored HIV Prevention Intervention for Single Young Men Who Have Sex With Men Who Meet Partners Online: Protocol for the myDEx Project.
Development of a Tailored HIV Prevention Intervention for Single Young Men Who Have Sex With Men Who Meet Partners Online: Protocol for the myDEx Project.
复制标题
DOI：
10.2196/resprot.7965
复制
发表时间：
2017-07-19
影响因子：
1.7
通讯作者：
Harper GW
中科院分区：
文献类型：
--
作者：
Bauermeister JA;Tingler RC;Demers M;Harper GW
18至24岁男男性行为者（YMSM）中人类免疫缺陷病毒（HIV）的新病例强调了对YMSM进行发育知情的HIV方案的重要性。我们开发了一种在线干预措施，重点关注不同性伴侣类型的风险降低策略。干预活动的重点是帮助青年男男性接触者反思其寻求伴侣的行为，制定性决策规则以降低其HIV风险，并考虑采取HIV预防行为。这项试点，随机对照试验（RCT）的目的是检查的可行性，可接受性，和初步疗效的定制，基于网络的艾滋病预防干预措施，为单一的YMSM。我们设计了一项在线招募的顺性别男性（N=180）的前瞻性RCT，这些男性报告最近无保护肛交，自我报告为HIV阴性或不知道自己的HIV状态，并通过在线约会应用程序认识性伴侣。对照组的个人接受注意力控制条件，其中包括目前在性教育网站上提供的艾滋病毒/性传播感染（STI）信息。干预组的个人接受一个6节的基于网络的计划，该计划根据他们的人口统计信息，寻求伴侣的行为和关系愿望，以及先前的性态度和行为量身定制。这一定制的内容将使艾滋病毒预防信息和安全性行为技能与YMSM在会见新伴侣时的预期结果相匹配，从而帮助他们考虑如何将安全性行为融入不同的伴侣类型。在基线、30天、60天和90天随访时进行研究评估。将在性风险行为和艾滋病毒/性传播感染检测中探讨干预的可接受性和初步疗效。RCT于2016年11月启动，目前正在进行中。迄今为止，已招募了180名符合条件的受试者，并提供了知情同意书和随机化。在干预组的120名个体中，51.7%（62/120）被确定为非西班牙裔白色人，对照组中有一半被确定为非西班牙裔白色人。在人种和/或种族、年龄或性取向方面未观察到组间差异。虽然有面对面的循证干预措施证明对YMSM有效，但在线提供的艾滋病毒/性传播感染预防干预措施很少。在线干预措施可以使青年男同性恋者更容易获得全面的艾滋病毒/性传播感染教育，并提供个性化的内容。我们开发的在线干预措施myDEx旨在通过利用量身定制的基于网络的内容来缩小YMSM在艾滋病毒预防方面的差距，目标是培养同性约会和建立关系的技能，同时降低他们感染艾滋病毒/性传播疾病的风险。ClinicalTrials.gov NCT 02842060; https://clinicaltrials.gov/ct2/show/NCT02842060（由WebCite在http：//www.webcitation.org/6rcJdxF9v上存档）
New cases of human immunodeficiency virus (HIV) among young men who have sex with men (YMSM), aged 18 to 24, underscore the importance of developmentally-informed HIV programs for YMSM. We developed an online intervention focused on risk reduction strategies across different sexual partner types. Intervention activities focus on assisting YMSM reflect on their partner-seeking behaviors, develop sexual decision-making rules to reduce their HIV risks, and consider the adoption of HIV prevention behaviors. This pilot, randomized controlled trial (RCT) aims to examine the feasibility, acceptability, and preliminary efficacy of a tailored, Web-based HIV prevention intervention for single YMSM. We designed a prospective RCT of online-recruited cis-gender men (N=180) who reported recent unprotected anal intercourse, self-report as HIV negative or are unaware of their HIV status, and meet sexual partners through online dating apps. Individuals in the control arm receive an attention-control condition that includes HIV/sexually transmitted infection (STI) information currently available on sex education websites. Individuals in the intervention arm receive a 6-session Web-based program tailored on their demographic information, partner-seeking behaviors and relationship desires, and prior sexual attitudes and behaviors. This tailored content will match HIV prevention messages and safer sex skills with YMSM’s outcome expectancies when meeting new partners and thereby help them consider how to integrate safer sex practices into different partner types. Study assessments are taken at baseline, 30-, 60-, and 90-day follow-ups. Intervention acceptability and preliminary efficacy will be explored in sexual risk behaviors and HIV/STI testing. The RCT launched in November 2016 and is ongoing. To date, 180 eligible individuals have been enrolled, consented, and randomized. Of the 120 individuals in the intervention arm, 51.7% (62/120) identify as non-Hispanic white and half of the control arm identifies as non-Hispanic white. There were no differences observed by arm for race and/or ethnicity, age, or sexual orientation. Although there are in-person evidence-based interventions with proven efficacy for YMSM, few HIV/STI prevention interventions delivered online exist. Online interventions may ease access to comprehensive HIV/STI education among YMSM and allow personalized content to be delivered. The online intervention that we developed, myDEx, aims to alleviate the gaps within HIV prevention for YMSM by utilizing tailored, Web-based content with the goal of developing skills for same-sex dating and relationship building, while reducing their risks for HIV/STI. ClinicalTrials.gov NCT02842060; https://clinicaltrials.gov/ct2/show/NCT02842060 (Archived by WebCite at http://www.webcitation.org/6rcJdxF9v)