Emerging therapies for the treatment of hepatitis C.
Emerging therapies for the treatment of hepatitis C.
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DOI:
10.1002/emmm.201303131
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发表时间:
2014-01
影响因子:
11.1
通讯作者:
Zeuzem S
中科院分区:
文献类型:
--
作者:
Lange CM;Jacobson IM;Rice CM;Zeuzem S
Opportunities to treat infection with hepatitis C virus (HCV) are evolving rapidly. From the introduction of interferon-α monotherapy in 1992 to the approval of telaprevir- and boceprevir-based triple therapies with pegylated interferon-α and ribavirin in 2011, the chances of curing patients infected with HCV genotype 1 have improved from <10% to approximately 70%. Significant further improvements are on the horizon, which may well cure virtually all hepatitis C patients with an all-oral, interferon-free regimen in the very near future. These exciting developments are reviewed in the present article.
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影响因子:
64.8
作者:
Brody, Herb
通讯作者:
Brody, Herb
影响因子:
168.9
作者:
Gane, Edward J.;Roberts, Stuart K.;Smith, Patrick F.
通讯作者:
Smith, Patrick F.
DOI:
10.1056/nejmoa1009482
发表时间:
2011-03-31
期刊:
The New England journal of medicine
影响因子:
--
作者:
Bacon BR;Gordon SC;Lawitz E;Marcellin P;Vierling JM;Zeuzem S;Poordad F;Goodman ZD;Sings HL;Boparai N;Burroughs M;Brass CA;Albrecht JK;Esteban R;HCV RESPOND-2 Investigators
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HCV RESPOND-2 Investigators
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158.5
作者:
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通讯作者:
Berrey, M. Michelle
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29.4
作者:
Chu, Tom W.;Kulkarni, Rohit;Shulman, Nancy S.
通讯作者:
Shulman, Nancy S.