ESOPHAGEAL-CARCINOMA - INITIAL RESULTS OF PALLIATIVE TREATMENT WITH COVERED SELF-EXPANDING ENDOPROSTHESES
ESOPHAGEAL-CARCINOMA - INITIAL RESULTS OF PALLIATIVE TREATMENT WITH COVERED SELF-EXPANDING ENDOPROSTHESES
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DOI：
10.1148/radiology.195.3.7538682
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发表时间：
1995-06-01
期刊：
影响因子：
19.7
通讯作者：
ADAM, A
中科院分区：
文献类型：
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作者：
WATKINSON, AF;ELLUL, J;ADAM, A
目得：为了评估的有效性的polyurethane复盖的自膨胀金属内假体在吞咽困难的救济由于irestablable esophageal carcinoma.MATERIALS和METHODS：32例（20名男性，12名女性）年龄41-89岁（中位数，70岁）与不可手术的食管癌进行支架置入术（44支架）。所有患者在治疗前后均进行了临床和影像学检查。结果：所有患者支架置入均成功，症状缓解良好，无严重并发症。11例患者由于早期部分迁移、晚期完全迁移、肿瘤过度生长或长狭窄而需要多枚支架。7例患者有相关的食管瘘或穿孔;支架插入后成功密封泄漏。治疗前平均吞咽困难评分为3.38 +/- 0.49（标准差），插入后3-4天为0.81 +/- 0.88。19例患者死亡，中位生存时间为78天（范围，12-245天），13例存活14-67天（中位数，30天）治疗后吞咽接近正常diet.CONCLUSION：插入塑料覆盖的内假体提供了快速，安全，有效的姑息恶性食管梗阻。
PURPOSE: To assess the effectiveness of a polyurethane-covered self-expanding metallic endoprosthesis in the relief of dysphagia due to irresectable esophageal carcinoma.MATERIALS AND METHODS: Thirty-two patients (20 men, 12 women) aged 41-89 years (median, 70 years) with inoperable esophageal carcinoma underwent stent placement (44 stents). All patients underwent both clinical and radiologic examination before and after treatment. Clinical follow-up was performed at 4-week intervals.RESULTS: Stent placement was successful in all patients, with good symptomatic relief and no serious complications. Eleven patients needed more than one stent because of early partial migration, late complete migration, tumor overgrowth, or long stricture. Seven patients had associated esophageal fistulization or perforation; leaks were successfully sealed after stent insertion. The mean dysphagia score was 3.38 +/- 0.49 (standard deviation) before treatment and 0.81 +/- 0.88 at 3-4 days after insertion. Nineteen patients died, with a median survival time of 78 days (range, 12-245 days), and 13 were alive 14-67 days (median, 30 days) after treatment and were swallowing a near normal diet.CONCLUSION: The insertion of plastic-covered endoprostheses provides rapid, safe, and effective palliation of malignant esophageal obstruction.