A questionnaire survey on attitude toward sperm cryopreservation among hematologists in Japan
A questionnaire survey on attitude toward sperm cryopreservation among hematologists in Japan
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日本血液科医生对精子冷冻保存态度的问卷调查
DOI：
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发表时间：
2017
影响因子：
2.1
通讯作者：
H. Okada
中科院分区：
文献类型：
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作者：
Tomohiro Kobayashi;T. Shin;Kojiro Nishio;Yukihito Shimomura;Toshiyuki Iwahata;Keisuke Suzuki;A. Miyata;Y. Kobori;G. Arai;H. Okada
多模式治疗的进展已导致癌症治疗结果的显著改善。现在有必要考虑癌症患者的整体生活质量。生育能力的保持是育龄期癌症幸存者最关心的问题。建议青春期后男性在治疗前进行精子冷冻保存，但许多患者在没有被告知生育力保存方案的情况下失去了生育力。为了确定精子冷冻保存在日本是如何被理解和实践的，我们调查了经常治疗年轻男性的血液学家。对45家主要血液学机构进行了精子冷冻保存的问卷调查。共有22个机构在截止日期前作出答复。除了一个机构外，所有机构都回答说，他们认为精子冷冻保存是必要的。只有15家机构回答说，他们告诉患者精子冷冻保存，12家机构回答说，他们在化疗前进行精子冷冻保存。在调查期间，共有213名年轻男性开始了他们的第一个化疗疗程，其中61人（28.6%）进行了精子冷冻保存。虽然几乎所有血液科医生都表示精子冷冻保存是保存生育能力的必要条件，但并不是所有的机构都向患者告知这一点。我们的研究结果表明，为了促进日本的生育能力保存，有必要将精子冷冻保存制度化，并建立医院间的网络。
Advances in multimodal treatment have led to dramatic improvement in cancer treatment outcomes. It is now necessary to consider cancer patients’ holistic quality of life. Fertility preservation is the top concern for cancer survivors of reproductive age. Sperm cryopreservation before treatment is recommended for postpubescent men, but many patients lose fertility without having been informed about options for fertility preservation. To determine how sperm cryopreservation is perceived and practiced in Japan, we surveyed hematologists who often treat young males. A questionnaire about sperm cryopreservation was sent to 45 major hematology institutions. A total of 22 institutions responded before the deadline. All institutions but one responded that they felt sperm cryopreservation is necessary. Only 15 institutions responded that they inform patients about sperm cryopreservation, and 12 institutions responded that they perform sperm cryopreservation before chemotherapy. A total of 213 young males started their first course of chemotherapy during the survey period, of whom 61 (28.6%) had their sperm cryopreserved. Although almost all hematologists stated that sperm cryopreservation is necessary for fertility preservation, not all institutions informed patients about it. Our findings indicate that, to promote fertility preservation in Japan, it will be necessary to systematize sperm cryopreservation and build inter-hospital networks.
影响因子：
45.3
作者：
Loren, Alison W.;Mangu, Pamela B.;Oktay, Kutluk
通讯作者：
Oktay, Kutluk