Alcohol, the reward system and dependence.
Alcohol, the reward system and dependence.
复制标题
酒精、奖励系统和依赖性。
DOI:
10.1007/978-3-0348-7330-7_11
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
Weiss,F
中科院分区:
文献类型:
--
作者:
Koob,GF;Rassnick,S;Heinrichs,S;Weiss,F
Evidence is presented to show that multiple neurotransmitter systems of the brain reward systems including GABA, glutamate, dopamine, serotonin and opioid peptides are involved in alcohol reinforcement. Dependence is associated with changes in many of these same systems, but also with changes in other neurotransmitters, such as brain corticotropin releasing factor. A midbrain forebrain circuitry that involves parts of thenucleus accumbensand amygdala is hypothesized to be the focus for the neuropharmacology of alcohol reinforcement.