TYROSINE KINASE RECEPTOR WITH EXTENSIVE HOMOLOGY TO EGF RECEPTOR SHARES CHROMOSOMAL LOCATION WITH NEU ONCOGENE
TYROSINE KINASE RECEPTOR WITH EXTENSIVE HOMOLOGY TO EGF RECEPTOR SHARES CHROMOSOMAL LOCATION WITH NEU ONCOGENE
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DOI：
10.1126/science.2999974
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发表时间：
1985-01-01
期刊：
影响因子：
56.9
通讯作者：
ULLRICH, A
中科院分区：
文献类型：
--
作者：
COUSSENS, L;YANGFENG, TL;ULLRICH, A
一种新的潜在的酪氨酸激酶基因家族的细胞表面受体已被确定和分子克隆的特点。它的一级序列与人表皮生长因子受体和v-erbB癌基因产物的一级序列非常相似;该蛋白基因的染色体位置与euconcogene一致，这表明这两个基因可能是相同的。
A novel potential cell surface receptor of the tyrosine kinase gene family has been identified and characterized by molecular cloning. Its primary sequence is very similar to that of the human epidermal growth factor receptor and the v-erbB oncogene product; the chromosomal location of the gene for this protein is coincident with theneuoncogene, which suggests that the two genes may be identical.