TOWARD UNDERSTANDING ETHANOLS CAPACITY TO BE REINFORCING - A CONDITIONED PLACE PREFERENCE FOLLOWING INJECTIONS OF ETHANOL
TOWARD UNDERSTANDING ETHANOLS CAPACITY TO BE REINFORCING - A CONDITIONED PLACE PREFERENCE FOLLOWING INJECTIONS OF ETHANOL
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DOI：
10.1016/0091-3057(85)90051-6
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发表时间：
1985-01-01
影响因子：
3.6
通讯作者：
HUBBELL, CL
中科院分区：
文献类型：
--
作者：
REID, LD;HUNTER, GA;HUBBELL, CL
先前每天消耗6%乙醇（ETOH）溶液26天的大鼠和没有这种历史的大鼠作为ETOH建立条件性位置偏好能力的测试的受试者。假定的预处理时间为注射ETOH（1 g/kg）后4 - 8 min。将假定的条件反射期设定为注射后不久，并使用习惯于饮用ETOH的大鼠，这两种方法的结合使得条件反射位置偏好在几次条件反射试验后就出现了。这样的结果可能揭示ETOH实现其增强能力的方式的特征，并为理解该增强的机制奠定基础。
Rats that had previously consumed a 6% ethanol (ETOH) solution daily for 26 days and rats without such a history served as subjects in a test for the ability of ETOH to establish a conditioned place preference. The time of putative conditioning was from 4 to 8 min after injections of ETOH, 1 g/kg. The combination of programming the period of putative conditioning to be shortly after injections and using rats habituated to drinking ETOH allowed a conditioned place preference to emerge after only a few conditioning trials. Such a result potentially reveals features of the way ETOH achieves its reinforcing capability and sets the stage for understanding the mechanism of that reinforcement.