Polyetheretherketone cages alone with allograft for three-level anterior cervical fusion.
Polyetheretherketone cages alone with allograft for three-level anterior cervical fusion.
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DOI：
10.5402/2012/452703
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Li H
中科院分区：
文献类型：
--
作者：
Liu H;Ploumis A;Li C;Yi X;Li H
共对25名患有退行性颈椎间盘疾病的连续患者进行了三节段颈椎前路椎间盘切除融合术（ACDF），包括填充同种异体移植物的聚醚醚酮（PEEK）融合器，随访至少两年。融合率达72%（18/25），6例患者出现无症状假关节，但屈伸X线片显示无活动度，无需翻修手术。在一个节段（C67）发生融合器下沉，但没有进展，无需再次手术。术后融合节段角度（FSA）和融合节段高度（FSH）显著增加（P < 0.001）。同样，术后日本骨科协会（乔亚）评分和视觉模拟量表（VAS）评分也有显著临床改善（P < 0.001）。PEEK椎间融合器联合同种异体移植物被证明是治疗三节段退行性颈椎间盘疾病的安全有效的手术选择。虽然融合率不高，但该技术可以改善颈椎的解剖结构并保持颈椎的矢状面。
A total of 25 consecutive patients suffering from degenerative cervical disc disease who underwent three-level anterior cervical discectomy and fusion (ACDF) including polyetheretherketone (PEEK) cages packed with allograft were followed up for at least two years. The fusion rate reached 72% (18/25), and asymptomatic pseudarthrosis was seen in 6 patients but without mobility on flexion-extension radiographs, and revision surgery was not needed. Cage subsidence occurred at one level (C67), but it was not progressive, and reoperation was not necessary. A significant increase (P < 0.001) in fused segment angle (FSA) and fused segment height (FSH) was observed postoperatively. Similarly, a significant clinical improvement (P < 0.001) was demonstrated postoperatively in terms of Japanese Orthopedic Association (JOA) score and visual analog scales (VASs) score. PEEK cages alone with allograft proved to be a safe and effective surgical option in the treatment of three-level degenerative cervical disc disease. Although the fusion rate was not high, this technique may offer improvement of symptomatology and maintenance of cervical spine's sagittal profile.